Indication for JANUVIA

+

Indication for JANUVIA

+
 

Got questions about JANUVIA?

Get the facts from our FAQs.

 
View Questions About JANUVIA® (sitagliptin) tablets
  • JANUVIA is a once-daily pill
  • Along with diet and exercise, it helps significantly lower blood sugar
  • JANUVIA, by itself, is not likely to cause blood sugar to go too low (hypoglycemia), because it works less when blood sugar is low
  • JANUVIA, by itself, is not likely to cause weight gain
  • JANUVIA is the #1 prescribed brandeda oral type 2 diabetes pillb

a Excludes generics.

b Source: IQVIA, NPA Monthly, TRx, Jan 2018–Jan 2019.

 Learn more about JANUVIA

Along with diet and exercise, JANUVIA works by enhancing your body’s own ability to lower blood sugar.

  • When your body senses blood sugar is high, JANUVIA works to help significantly lower it
  • And when your body senses blood sugar is low, JANUVIA works less
  • JANUVIA works more when you need it, and less when you don't

 Learn more about how JANUVIA works

Take JANUVIA one time a day exactly as your doctor tells you. You can take JANUVIA with or without food. Click below for more information.

 Learn more about taking JANUVIA

JANUVIA, by itself, is not likely to cause blood sugar going too low (known as hypoglycemia) because it works less when your blood sugar is low. If you take JANUVIA with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher. Your doctor may lower the dose of your sulfonylurea medicine or insulin while you use JANUVIA. See Important Safety Information to learn more.

Yes. Making smart food choices and being physically active are important ways to manage blood sugar levels. A well-balanced diet is one part of a healthy lifestyle for people with type 2 diabetes. Thirty minutes of exercise—such as a brisk walk—most days of the week is recommended.

Always talk to your doctor before starting an exercise program.

JANUVIA, by itself, is not likely to cause weight gain. Keeping at a healthy weight is an important part of managing diabetes.

JANUVIA should not be used in patients with type 1 diabetes or with diabetic ketoacidosis (increased ketones in the blood or urine). If you have had pancreatitis (inflammation of the pancreas), it is not known if you have a higher chance of getting it while taking JANUVIA.

Do not take JANUVIA if you are allergic to any of the ingredients in JANUVIA. See question below for a complete list of ingredients in JANUVIA.

Symptoms of a serious allergic reaction to JANUVIA may include rash, raised red patches on your skin (hives), or swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing.

Serious side effects can happen in people taking JANUVIA, including:

  • Inflammation of the pancreas (pancreatitis) which may be severe and lead to death. Certain medical problems make you more likely to get pancreatitis

    Before you start taking JANUVIA, tell your doctor if you have ever had:

    • pancreatitis
    • high blood triglyceride levels
    • stones in your gallbladder (gallstones)
    • kidney problems
    • a history of alcoholism

    Stop taking JANUVIA and call your doctor right away if you have pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen through to your back. The pain may happen with or without vomiting. These may be symptoms of pancreatitis.

  • Heart failure. Heart failure means your heart does not pump blood well enough

    Before you start taking JANUVIA, tell your doctor if you have ever had heart failure or have problems with your kidneys. Contact your doctor right away if you have any of the following symptoms:

    • increasing shortness of breath or trouble breathing, especially when you lie down
    • swelling or fluid retention, especially in the feet, ankles or legs
    • an unusually fast increase in weight
    • unusual tiredness

    These may be symptoms of heat failure.

  • Possible side effects of JANUVIA

    Serious side effects have happened in people taking JANUVIA. See above.

  • Low blood sugar (hypoglycemia). If you take JANUVIA with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher. The dose of your sulfonylurea medicine or insulin may need to be lowered while you use JANUVIA. Signs and symptoms of low blood sugar may include:
    • headache
    • drowsiness
    • irritability
    • hunger
    • dizziness
    • confusion
    • sweating
    • feeling jittery
    • weakness
    • fast heart beat
  • Serious allergic reactions. If you have any symptoms of a serious allergic reaction, stop taking JANUVIA and call your doctor right away. Your doctor may give you a medicine for your allergic reaction and prescribe a different medicine for your diabetes
  • Kidney problems, sometimes requiring dialysis
  • Joint pain. Some people who take medicines called DPP-4 inhibitors like JANUVIA may develop joint pain that can be severe. Call your doctor if you have severe joint pain
  • Skin reaction. Some people who take medicines called DPP-4 inhibitors like JANUVIA may develop a skin reaction called bullous pemphigoid that can require treatment in a hospital. Tell your doctor right away if you develop blisters or the breakdown of the outer layer of your skin (erosion). Your doctor may tell you to stop taking JANUVIA

The most common side effects of JANUVIA include upper respiratory infection, stuffy or runny nose and sore throat, and headache.

JANUVIA may have other side effects, including stomach upset and diarrhea, swelling of the hands or legs, when JANUVIA is used with rosiglitazone (Avandia®). Rosiglitazone is another type of diabetes medicine.

These are not all the possible side effects of JANUVIA. For more information, ask your doctor or pharmacist.

Tell your doctor if you have any side effect that bothers you, is unusual or does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Before you take JANUVIA, tell your doctor if you:

  • Have or have had inflammation of your pancreas (pancreatitis)
  • Have kidney problems
  • Have any other medical conditions
  • Are pregnant or plan to become pregnant. It is not known if JANUVIA will harm your unborn baby. If you are pregnant, talk with your doctor about the best way to control your blood sugar while you are pregnantPregnancy Registry: If you take JANUVIA at any time during your pregnancy, talk with your doctor about how you can join the JANUVIA pregnancy registry. The purpose of this registry is to collect information about the health of you and your baby. You can enroll in this registry by calling 1-800-986-8999.
  • Are breast-feeding or plan to breast-feed. It is not known if JANUVIA will pass into your breast milk. Talk with your doctor about the best way to feed your baby if you are taking JANUVIA

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Know the medicines you take. Keep a list of your medicines and show it to your doctor and pharmacist when you get a new medicine.

If you miss a dose, take it as soon as you remember. If you do not remember until it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses of JANUVIA at the same time.

The active ingredient in JANUVIA is sitagliptin. Other inactive ingredients include microcrystalline cellulose, anhydrous dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, and sodium stearyl fumarate. The tablet film coating contains the following inactive ingredients: polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide, red iron oxide, and yellow iron oxide.

Yes. Eligible, privately insured patients may pay as little as $5 per prescription on each of up to 12 qualifying prescriptions. Maximum savings is $150 per prescription. Not all patients are eligible. Certain restrictions apply. Please see the Savings Offer page for Terms and Conditions.

You should store JANUVIA at 68°F to 77°F (20°C to 25°C). You can also keep JANUVIA in a pill organizer and store it in a safe place. Keep JANUVIA, and all medicines, out of the reach of children.

JANUVIA should not be cut in half or crushed, and should be taken as prescribed by your doctor.

Whether you’ve just started taking JANUVIA or have been taking it, think of your doctor as your partner who is there to help answer your questions. You can use the Questions for Your Doctor guide to help get the conversation started.

Type 2 diabetes is a condition in which your body does not make enough insulin, and the insulin that your body produces does not work as well as it should. Your body can also make too much sugar. When this happens, sugar (glucose) builds up in the blood. This can lead to serious medical problems. High blood sugar can be lowered by diet and exercise, and by certain medicines when necessary.

 Learn more about type 2 diabetes

The A1C test measures the average amount of sugar that has been in your blood over the past 2 to 3 months. The American Diabetes Association recommends an A1C goal of less than 7% for many adults with diabetes. The A1C goal for some people may need to be higher or lower. Ask your doctor what A1C goal is right for you.

Managing type 2 diabetes includes taking your medicines exactly as your doctor prescribes, making healthy food choices, and being physically active.


Important Safety Information